The P-Shot is a name used for penile platelet-rich plasma injections. It is being studied for erectile dysfunction and related concerns, but current evidence does not support presenting it as a proven or routine treatment. At Mayflower Clinic, the first priority is a private medical assessment, honest discussion of uncertainty and comparison with established options.
Male sexual-health concerns are discussed in a discreet consultation setting. Messages and records are handled as confidential medical information. WhatsApp can be used to arrange an appointment, but avoid sending intimate photographs or detailed medical records through an ordinary message unless the clinic has specifically provided a secure, consent-based process.
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Clinical studies have reported mixed findings, and recent reviews continue to identify small sample sizes, variable PRP preparation, inconsistent injection schedules and uncertain durability. Current European guidance states that evidence remains insufficient to recommend PRP for routine erectile-dysfunction treatment. The page therefore avoids promising faster erections, increased sensation, penile enlargement, a fixed success rate or a 12–18 month duration.
Platelet-rich plasma is prepared by collecting a blood sample and using centrifugation to separate a plasma fraction with a higher platelet concentration than ordinary blood. Platelets contain signalling proteins involved in clotting and tissue-repair pathways. This biological rationale has led researchers to study PRP in many fields, including sexual medicine.
For the P-Shot, the prepared PRP is injected into penile tissue. However, a plausible biological mechanism is not the same as proven clinical benefit. Studies differ in platelet concentration, activation method, injection sites, number of sessions and outcome measurement. This makes it difficult to define the best protocol or reliably predict who will benefit.
At Mayflower Clinic, consultation focuses first on the actual concern and its possible cause. If penile PRP is discussed, it is framed as an investigational option with informed consent—not as a replacement for cardiovascular evaluation, established ED treatment or specialist referral where indicated.
A medically responsible webpage should separate the procedure concept from marketing claims.
Erection difficulty is a symptom, not a single diagnosis. Treatment choice depends on the cause, severity, health risks and previous response.
Onset, consistency, morning erections, sexual desire, ejaculation, pain, curvature and previous treatment response help define the problem.
Diabetes, blood pressure, cholesterol, heart disease, neurological conditions, pelvic surgery and medicines can affect erectile function.
Persistent ED can be associated with vascular disease. The consultation may identify a need for broader medical or cardiac evaluation.
Selected patients may need early-morning testosterone or additional tests based on symptoms and examination—not automatic hormone treatment.
Stress, performance anxiety, depression and relationship strain may contribute alone or together with physical causes.
Evidence-based options are reviewed before an investigational restorative therapy is considered.
This is not a self-selection checklist. Final suitability requires individual medical assessment.
The process begins with diagnosis and consent—not with an automatic injection package.
Discuss the concern, duration, medical history, medicines, previous treatment and expectations in a confidential setting.
Examination, blood pressure and selected tests may be advised. Referral may be recommended when cardiovascular, endocrine, neurological or urological assessment is needed.
Benefits, limitations, contraindications and costs of medicines, devices, specialist injections, counselling or surgery are discussed alongside the investigational status of PRP.
Consent should state that benefit is uncertain, protocols are not standardized, results are not guaranteed and additional treatment may still be required.
A blood sample is processed to prepare PRP. Sterility, identification and clinical documentation are maintained throughout the procedure.
If proceeding, local or topical anaesthesia is used as appropriate, followed by sterile injection by the treating doctor according to the selected protocol.
Follow-up checks injection-site recovery, adverse effects and symptom change. Lack of benefit should lead to reassessment rather than repeated procedures without a clear rationale.
Exact advice depends on the protocol and individual health. Follow the written instructions provided after treatment.
Temporary tenderness, bruising, swelling or minor spotting at an injection point may occur. These should gradually settle rather than worsen.
Keep the area clean and follow the clinic's instructions about bathing, strenuous exercise, sexual activity and medicines after the procedure.
Report increasing pain, spreading redness, fever, discharge, significant bleeding, rapidly increasing swelling or any symptom that feels unusual.
The most appropriate option depends on cause, medical safety, response to previous treatment and patient preference.
| Option | Evidence status | Typical role | Important considerations |
|---|---|---|---|
| Lifestyle and risk-factor care | Established | Addresses smoking, inactivity, obesity, diabetes, blood pressure, cholesterol and sleep where relevant. | Benefits general and vascular health; improvement may take time and may need other ED treatment. |
| Psychosexual support | Established when indicated | Useful for anxiety, relationship factors, depression or mixed physical and psychological ED. | May be combined with medical treatment. |
| Prescription PDE5 inhibitor | Established | Common first-line medicine when medically suitable. | Requires medication and cardiovascular review; must not be combined with nitrate medicines. |
| Vacuum erection device | Established | Non-surgical mechanical option when medicines are unsuitable, ineffective or not preferred. | Needs correct sizing, instruction and realistic expectations. |
| Specialist injection therapy | Established | May be considered when tablets are ineffective or unsuitable. | Requires supervised teaching and counselling about priapism and other risks. |
| Penile implant surgery | Established for selected patients | Considered after failure, unsuitability or rejection of less-invasive options. | Irreversible surgery with infection, device and recovery considerations. |
| Penile PRP / P-Shot | Investigational | Restorative therapy under study; not recommended as routine ED treatment by current EAU guidance. | No standardized preparation, dose, session number or proven duration of benefit. |
For a complete overview, read the Erectile Dysfunction Treatment in Nagpur guide.
“A regenerative procedure should never distract from diagnosing why erectile difficulty is occurring. My responsibility is to explain what is established, what remains investigational, what the realistic alternatives are and whether doing nothing invasive is the better decision.”Dr. Pawan Shahane, M.Ch. Plastic Surgery · Founder, Mayflower Clinic, Nagpur
A public fixed price can be misleading when evaluation, investigations and protocol may differ.
Clinical review may identify tests or another treatment pathway before PRP is considered.
Collection system, processing method and disposables influence procedure cost.
No standard evidence-based session package exists; follow-up should be clinically justified.
Management of diabetes, hormones, psychological factors or established ED therapy may be more important than PRP itself.
A transparent quote is provided after consultation, with the included services explained. Payment does not guarantee a clinical result.
These visible questions match the FAQ structured data on this page.
Bring a list of current medicines and any recent diabetes, cholesterol, hormone or heart-related reports. A consultation does not commit you to a procedure.
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