Penile Botox in Nagpur
Clinically Precise Treatment for
Premature Ejaculation
Botulinum toxin type A (Botox) micro-injection into the glans penis modulates glanular hypersensitivity — the key physiological driver of rapid ejaculation. Non-surgical. No incisions. No hospital stay. Performed personally by Dr. Pawan Shahane, M.Ch.


What Is Penile Botox, and How Does It Work?
Penile Botox refers to the controlled, clinical injection of purified botulinum toxin type A into the glans penis — the primary site of sensory concentration responsible for triggering the ejaculatory reflex.
Premature ejaculation (PE) is one of the most common male sexual health concerns, affecting an estimated 30–40% of men at some point. One well-established physiological component is glanular hypersensitivity: the glans generating neural impulses that rapidly exceed the threshold required to initiate ejaculation.
Botulinum toxin temporarily reduces neurotransmitter release at the injected nerve endings, lowering the sensitivity of the glans below its pathologically elevated baseline — without permanently altering anatomy, erection, or overall sensation.
The procedure does not target the erectile mechanism. Blood flow, rigidity, and arousal are unaffected. Only the hypersensitive neural pathway responsible for premature triggering is modulated.
Onset of effect: 5–7 days post-injection. Maximum benefit: 2 weeks. Duration: 4–6 months. The procedure can be safely repeated.
Who Should Consider Penile Botox?
This procedure is suitable for men with documented or self-assessed rapid ejaculation attributable to physiological hypersensitivity, particularly when conventional approaches have been unsatisfactory.
Premature Ejaculation (Primary)
Men who have experienced rapid ejaculation since their first sexual encounters — often with a strong physiological basis including documented glanular hypersensitivity.
Premature Ejaculation (Secondary)
Men who have developed PE after a period of normal ejaculatory function — commonly following periods of abstinence, anxiety, or relationship changes.
Glanular Hypersensitivity
Men with excessive glans sensitivity causing discomfort or difficulty with intravaginal containment, even in the absence of classical PE diagnosis.
Inadequate Response to Topical Agents
Men who find desensitising creams or sprays inconvenient, unreliable, or causing unwanted sensitivity reduction in their partner.
Preference to Avoid Systemic Medication
Men who are not candidates for or do not wish to use oral dapoxetine or SSRIs due to systemic side effects or contraindications.
Post-Circumcision Hypersensitivity
Men who have undergone circumcision and experience heightened glans sensitivity due to reduced protective cover of the mucosal surface.
How Penile Botox Is Performed at Mayflower Clinic
A structured, four-stage clinical process — from assessment to full effect. No surprises, no shortcuts.
Consultation & Assessment
Dr. Shahane personally reviews your medical history, assesses ejaculatory pattern, excludes psychological or vascular contributors, and confirms physiological hypersensitivity as the primary aetiology.
Topical Anaesthesia
A lidocaine-based topical anaesthetic cream is applied to the glans and left to act for 30–45 minutes. This ensures the procedure is comfortable throughout, with minimal to no pain reported by most patients.
Micro-Injection
A precisely calculated dose of botulinum toxin type A is administered via a series of small-gauge micro-injections into the dorsal glans. The injection sequence takes 10–15 minutes. No incisions, no sutures.
Post-Procedure & Review
You rest briefly and then return home the same day. A follow-up is scheduled at 7–10 days to assess initial response. Full effect is typically established at 2 weeks post-procedure.
How Botulinum Toxin Modulates Ejaculatory Sensitivity
The glans penis contains a dense concentration of sensory nerve endings — Meissner's corpuscles and free nerve endings — that transmit tactile signals to the spinal ejaculatory generator.
When these nerve endings are hypersensitive, even moderate stimulation can rapidly summate above the ejaculatory threshold, causing premature triggering of the ejaculatory reflex.
Botulinum toxin type A inhibits acetylcholine release at neuromuscular junctions and reduces neuropeptide transmission at sensory nerve endings at the injection site.
The result is temporary reduction in sensory signal intensity from the glans, raising the effective stimulation threshold needed to initiate the ejaculatory cascade.
Erection is unaffected — the erectile mechanism involves separate vascular and smooth muscle pathways in the corpora cavernosa, not targeted by this injection technique.
The effect is fully reversible — as the toxin is metabolised over 4–6 months, sensory function returns to its pre-treatment baseline completely.
Penile Botox vs. Other PE Treatments
Key Benefits of Penile Botox Treatment
Non-Surgical
No incisions, no sutures, no scarring. A needle-only technique requiring no operating theatre.
Day-Care Convenience
Completed in approximately 20–30 minutes. You return home the same day with no hospital admission.
Fully Reversible
All effects are temporary. The toxin is metabolised naturally over 4–6 months. No permanent changes.
No Systemic Side Effects
Acts locally at the injection site. No systemic drug interactions, mood effects, or cardiovascular concerns.
Consistent Duration
A single treatment provides consistent effect for 4–6 months — no pre-activity preparation or timing required.
No Partner Impact
Unlike topical agents, there is zero risk of sensitivity transfer to a partner.
Recovery & Effect Timeline
Procedure Day
30–40 min at clinic. Topical anaesthesia + injections. Return home same day. Minor sensitivity at injection site resolves within 24 hours.
Days 5–7
Initial onset of effect — reduced glanular sensitivity and early improvement in ejaculatory control begin to be noticed.
Week 2
Full therapeutic effect established. Follow-up review with Dr. Shahane. Assessment of response and documentation of outcome.
Months 4–6
Effect gradually diminishes as the toxin is metabolised. Re-treatment can be scheduled when required. Duration varies by individual.
Post-Procedure Guidance: Avoid vigorous sexual activity for 5–7 days following the procedure to allow the toxin to settle optimally. Dr. Shahane will provide full written post-care instructions at your appointment.
Why Choose Dr. Pawan Shahane for Penile Botox in Nagpur?
Dr. Shahane holds an M.Ch. in Plastic Surgery from SSG Hospital, Baroda — a superspecialty degree requiring rigorous residency training in precise tissue and injection techniques. Very few practitioners in Central India hold this qualification.
Dr. Shahane personally conducts every consultation, performs every assessment, and carries out every procedure. You will not be managed by a junior clinician, assistant, or technician at any stage.
All records, communications, and appointments for male intimate health concerns are managed with absolute privacy. The clinic's confidentiality standards are aligned with the Digital Personal Data Protection Act 2023 (India).
Recognised as one of the three best plastic surgeons in Nagpur for nine consecutive years through independent patient-review verification. A sustained record, not a one-time distinction.
Consultations for intimate health concerns are conducted with sensitivity and respect. Dr. Shahane is known for plain-spoken, honest explanations and never pressures patients into any treatment decision.
Patients travel to Mayflower Clinic from Amravati, Wardha, Yavatmal, Akola, Gondia, Raipur, and Bilaspur for procedures and consultations not readily available locally.
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Learn About P-Shot →Penile Fillers (HA Girth Enhancement)
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Learn About Penile Fillers →Cosmetic Gynaecology (FCGS)
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View FCGS Procedures →Frequently Asked Questions
Honest, detailed answers to the questions patients most commonly ask about Penile Botox treatment.
What exactly is Penile Botox and how does it address premature ejaculation?
Is the procedure painful? Will I need general anaesthesia?
How long does the effect of Penile Botox last?
Will Penile Botox affect erections or cause permanent sensitivity loss?
How is Penile Botox different from desensitising sprays or creams?
Is this consultation completely confidential?
Will Dr. Pawan Shahane personally assess and perform the procedure?
Begin with a Private, Confidential Consultation
Every journey begins with an honest conversation. Reach out to Dr. Pawan Shahane's team through the channel you're most comfortable with. All enquiries for intimate health concerns are handled privately and discreetly.
Mon–Sat | 11:00 AM – 6:00 PM | Dhantoli, Nagpur | contact@mayflowerclinic.in
Medical Disclaimer: The information on this page is for general educational purposes only and does not constitute medical advice. Individual outcomes vary. This page does not replace a formal clinical consultation. Please discuss your specific medical history, expectations, risks, and alternatives directly with Dr. Pawan Shahane before making any treatment decision. All procedures carry inherent risks, and individual outcomes vary significantly based on patient anatomy, general health, and adherence to post-procedure instructions. Mayflower Clinic, Dhantoli, Nagpur.


